It's the second time the Leeds shop has been targeted this year.
Police are appealing for information following a ram-raid burglary at the Louis Vuitton store in Leeds city centre on Wednesday night.
At 9.40pm police received reports a black Saab estate being reversed into the shop in Briggate to gain entry through the previously boarded-up frontage and steal goods on display.
The Saab, registration W148VGO, was left at the scene and the suspects, described as seven to eight masked males, drove off in a white Volkswagen Golf and a white Ford Focus C-max.
Those vehicles, which were stolen and bearing false registration plates, were found abandoned at various locations in east Leeds and have been recovered for forensic examination along with a connected white Ford Connect van.
Detective Inspector Phil Jackson, of Leeds District CID, said: "This business was previously targeted in the same way on April 9 and this has again been a planned and organised offence targeting high value goods in the store.
"We are conducting extensive enquiries to identify the suspects and it is too early to say if there is a definite link to the previous incident, which is also still under investigation.
"We have spoken to a number of witnesses but are still keen to hear from anyone who witnessed this incident, particularly if they filmed it on their phones.
"We are still getting details of what has been taken but we would like to hear from anyone who has been offered Louis Vuitton goods for sale in suspicious circumstances.
"Clearly this is the second time these premises have been targeted over a short period of time and we appreciate the impact this will have had on the business. We will be liaising with them to look at what additional security measures can be put in place.
"We recognise that another offence like this so soon after the previous one will have caused understandable concern among those living and working in the city centre, and our colleagues in the city neighbourhood team will be working to provide suitable support and reassurance to businesses and the community."