It happened last night when a VW Golf and Land Rover collided.
Police are appealing for witnesses after a two vehicle collision in Queensbury, Bradford.
Officers were called at 22.33 last night by the ambulance service to Brighouse and Denholme Road at the junction with Perseverance Road.
A 72 year old man suffered serious injuries and was taken to Leeds General Infirmary.
The collision involved a grey Volkwagen Golf and red Land Rover.
Four men have been arrested on suspicion of causing serious injury by dangerous driving and remain in custody at this time.
Police would like to appeal to anyone who witnessed the collision or who saw the vehicles prior to the collision or may have any dash cam or CCTV footage to get in touch.
Information can be given via 101 or use the live chat facility at www.westyorkshire.police.uk/contactus quoting log 1915 of July 15